Effects of Salbutamol and Furosemide in The Treatment of Transient Tachypnea of Newborn - A Randomized Controlled Trial

نویسندگان

چکیده

Objective: To assess and compare the effect of Salbutamol Furosemide therapy in management transient tachypnea newborn.
 Study Design: Randomized controlled trial (Registered with Clinical Trials.gov: NCT03208894).
 Place Duration Study: Neonatal Intensive Care Unit Pakistan Emirates Military Hospital Rawalpindi from Oct 2019 to May 2020.
 Methodology: A total 100 newborns were included study. They divided into 4 groups. Group-A received nebulized 0.1ml Salbutamol. Group-B was given single intravenous dose injection at 2mg per kg. Group-C both IV Control group-D only supportive care.
 Results: There 48 male babies 52 female babies. The average gestational age 38.8 ± 6.2 weeks birth weight 2558 620 grams. Administration together (group-C) showed significant reduction mean duration oxygen dependency compared control-group (13.40 3.342 vs 83.64 68.546 hours respectively (p<0.001), as well need for mechanical ventilation. other two groups (A B) also reduced control group, but results not statistically significant.
 Conclusion: when tend reduce invasive ventilation newborn.

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Effects of Salbutamol on the Treatment of Transient Tachypnea of the Newborn

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ژورنال

عنوان ژورنال: Pakistan Armed Forces Medical Journal

سال: 2022

ISSN: ['2411-8842', '0030-9648']

DOI: https://doi.org/10.51253/pafmj.v72i1.6076